Prescription of Benzodiazepines Continues to Decline in Germany

This year again I want to publish some comments on the development of the pharmaceutical market in Germany.  The figures for 2012 were presented recently in the Drug Prescription Report 2013 (Arzneiverordnungsreport 2013, edited by U. Schwabe and D. Paffrath, Springer-Verlag 2013). Continue reading

Suvorexant: The Perfect Hypnotic?

In the issue of Science Translational Medicine published on April 3, 2013, Uslaner et al.  of the American pharmaceutical company Merck report on a new class of hypnotics, which are characterized by a completely new mechanism of action (Uslaner et al., Sci Transl Med 2013). It is called DORA (dual orexin receptor antagonists). In an editorial in the issue of Science published on April 5, 2013, Emmanuel Mignot of Stanford University in California asks the question whether a DORA could be “The Perfect Hypnotic?” (Mignot, Science 2013). Continue reading